DF/HCC Cancer Proteomics Core

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Dana Farber/Harvard Cancer Center

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Proteomic Services Offered

The Proteomics Core will provide a comprehensive array of services pertaining to the design, performance and analysis of proteomic studies carried out with a wide range of technologies.

  • Profile proteins in biological fluids and tissues
  • Quantitate proteins
  • Identify proteins and their posttranslational modifications
  • Study protein-protein interactions

 

Bioinformatics Analyses

  • Personalized consulting
  • Customized data analysis and interpretation
  • Web-based bioinformatics tools
  • Comprehensive and innovative Bioinformatics and visualization tools
  • Comprehensive annotation tools
  • Identification of Global Relationships
  • Incorporation of Biological Knowledge
  • Pathway Analysis
  • Publication ready figures

The Bioinformatics Core is also responsible for software support and development

The Bioinformatics Core will be the central portal of the Proteomics Core that will provide DF/HCC investigators with access to phenotypically annotated proteomics data as well as a large set of analytic procedures (i.e. unsupervised and supervised learning techniques, statistical analysis tools, automated clustering and classification procedures, pathway analysis and generation tools, protein identification database tools, data-visualization tools, annotation tools) with which to explore the data sets for further hypothesis generation.

Finally, a consultative service provided by key members of the core will be available at all times for DF/HCC investigators to assess the rationale and feasibility for undertaking specific projects, designing proteomic studies, process and protocol development, proteomic data analysis, and the interpretation of results.

 

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